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Autophagy balances mtDNA synthesis and degradation by DNA polymerase POLG during starvation
Mitochondria contain tens to thousands of copies of their own genome (mitochondrial DNA [mtDNA]), creating genetic redundancy capable of buffering mutations in mitochondrial genes essential for cellular function. However, the mechanisms regulating mtDNA copy number have been elusive. Here we found t...
Tallennettuna:
| Julkaisussa: | J Cell Biol |
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| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Rockefeller University Press
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940314/ https://ncbi.nlm.nih.gov/pubmed/29519802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201801168 |
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