CAG Repeat Variants in the POLG1 Gene Encoding mtDNA Polymerase-Gamma and Risk of Breast Cancer in African-American Women

The DNA polymerase-gamma (POLG) gene, which encodes the catalytic subunit of enzyme responsible for directing mitochondrial DNA replication in humans, contains a polyglutamine tract encoded by CAG repeats of varying length. The length of the CAG repeat has been associated with the risk of testicular...

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Detalhes bibliográficos
Main Authors: Azrak, Sami, Ayyasamy, Vanniarajan, Zirpoli, Gary, Ambrosone, Christine, Bandera, Elisa V., Bovbjerg, Dana H., Jandorf, Lina, Ciupak, Gregory, Davis, Warren, Pawlish, Karen S., Liang, Ping, Singh, Keshav
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262786/
https://ncbi.nlm.nih.gov/pubmed/22276120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029548
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