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p53 regulates mtDNA copy number and mitocheckpoint pathway
BACKGROUND: We previously hypothesized a role for mitochondria damage checkpoint (mito-checkpoint) in maintaining the mitochondrial integrity of cells. Consistent with this hypothesis, defects in mitochondria have been demonstrated to cause genetic and epigenetic changes in the nuclear DNA, resistan...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Medknow Publications
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2687143/ https://ncbi.nlm.nih.gov/pubmed/19439913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.50893 |
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