Rearrangements of Human Mitochondrial DNA (mtDNA): New Insights into the Regulation of mtDNA Copy Number and Gene Expression

Mitochondria from patients with Kearns–Sayre syndrome harboring large-scale rearrangements of human mitochondrial DNA (mtDNA; both partial deletions and a partial duplication) were introduced into human cells lacking endogenous mtDNA. Cytoplasmic hybrids containing 100% wild-type mtDNA, 100% mtDNA w...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Tang, Yingying, Schon, Eric A., Wilichowski, Ekkehard, Vazquez-Memije, Martel E., Davidson, Edgar, King, Michael P.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 2000
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14860/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10749943/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.4.1471
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