Dysregulation of sphingolipid metabolism contributes to bortezomib-induced neuropathic pain

The development of chemotherapy-induced painful peripheral neuropathy is a major dose-limiting side effect of many chemotherapeutics, including bortezomib, but the mechanisms remain poorly understood. We now report that bortezomib causes the dysregulation of de novo sphingolipid metabolism in the sp...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Exp Med
Hauptverfasser: Stockstill, Katherine, Doyle, Timothy M., Yan, Xisheng, Chen, Zhoumou, Janes, Kali, Little, Joshua W., Braden, Kathryn, Lauro, Filomena, Giancotti, Luigino Antonio, Harada, Caron Mitsue, Yadav, Ruchi, Xiao, Wen Hua, Lionberger, Jack M., Neumann, William L., Bennett, Gary J., Weng, Han-Rong, Spiegel, Sarah, Salvemini, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2018
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940258/
https://ncbi.nlm.nih.gov/pubmed/29703731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170584
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge