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Full and partial agonists evoke distinct structural changes in opening the muscle acetylcholine receptor channel

The muscle acetylcholine (ACh) receptor transduces a chemical into an electrical signal, but the efficiency of transduction, or efficacy, depends on the particular agonist. It is often presumed that full and partial agonists elicit the same structural changes after occupancy of their binding sites b...

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Detaylı Bibliyografya
Yayımlandı:J Gen Physiol
Asıl Yazarlar: Mukhtasimova, Nuriya, Sine, Steven M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Rockefeller University Press 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940249/
https://ncbi.nlm.nih.gov/pubmed/29680816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711881
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