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Full and partial agonists evoke distinct structural changes in opening the muscle acetylcholine receptor channel

The muscle acetylcholine (ACh) receptor transduces a chemical into an electrical signal, but the efficiency of transduction, or efficacy, depends on the particular agonist. It is often presumed that full and partial agonists elicit the same structural changes after occupancy of their binding sites b...

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Bibliografske podrobnosti
izdano v:J Gen Physiol
Main Authors: Mukhtasimova, Nuriya, Sine, Steven M.
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940249/
https://ncbi.nlm.nih.gov/pubmed/29680816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711881
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