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Full and partial agonists evoke distinct structural changes in opening the muscle acetylcholine receptor channel
The muscle acetylcholine (ACh) receptor transduces a chemical into an electrical signal, but the efficiency of transduction, or efficacy, depends on the particular agonist. It is often presumed that full and partial agonists elicit the same structural changes after occupancy of their binding sites b...
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| Publicado no: | J Gen Physiol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940249/ https://ncbi.nlm.nih.gov/pubmed/29680816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711881 |
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