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Different chromatin and DNA sequence characteristics define glucocorticoid receptor binding sites that are blocked or not blocked by coregulator Hic-5

The glucocorticoid receptor (GR) regulates genes in many physiological pathways by binding to enhancer and silencer elements of target genes, where it recruits coregulator proteins that remodel chromatin and regulate the assembly of transcription complexes. The coregulator Hydrogen peroxide-inducibl...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee, Brian H., Stallcup, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940187/
https://ncbi.nlm.nih.gov/pubmed/29738565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196965
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