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Glucocorticoid receptor binding to chromatin is selectively controlled by the coregulator Hic-5 and chromatin remodeling enzymes

The steroid hormone-activated glucocorticoid receptor (GR) regulates cellular stress pathways by binding to genomic regulatory elements of target genes and recruiting coregulator proteins to remodel chromatin and regulate transcription complex assembly. The coregulator hydrogen peroxide-inducible cl...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lee, Brian H., Stallcup, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454112/
https://ncbi.nlm.nih.gov/pubmed/28381557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.782607
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