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Selective Coregulator Function and Restriction of Steroid Receptor Chromatin Occupancy by Hic-5

Steroid receptors (SRs) bind specific DNA regulatory sequences, thereby activating and repressing gene expression. We previously showed that transcriptional coregulator Hic-5 facilitates glucocorticoid regulation of some genes but blocks glucocorticoid regulation of others. Here, in a genome-wide an...

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Publicat a:Mol Endocrinol
Autors principals: Chodankar, Rajas, Wu, Dai-Ying, Gerke, Daniel S., Stallcup, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415210/
https://ncbi.nlm.nih.gov/pubmed/25763609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1403
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