MYSM1 Is Essential for Maintaining Hematopoietic Stem Cell (HSC) Quiescence and Survival

BACKGROUND: Histone H2A deubiquitinase MYSM1 has recently been shown to be essential for hematopoiesis and hematopoietic stem cell (HSC) function in both mice and humans. However, conventional MYSM1 knockouts cause partial embryonic lethality and growth retardation, and it is difficult to convincing...

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Bibliografische gegevens
Gepubliceerd in:Med Sci Monit
Hoofdauteurs: Huo, Yi, Li, Bing-Yi, Lin, Zhi-Feng, Wang, Wei, Jiang, Xiao-Xia, Chen, Xu, Xi, Wen-Jin, Li, Yu-Fang, Yang, An-Gang, Chen, Si-Yi, Wang, Tao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: International Scientific Literature, Inc. 2018
Onderwerpen:
Lab/In Vitro Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939948/
https://ncbi.nlm.nih.gov/pubmed/29694335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.906876
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