MYSM1 Is Essential for Maintaining Hematopoietic Stem Cell (HSC) Quiescence and Survival

BACKGROUND: Histone H2A deubiquitinase MYSM1 has recently been shown to be essential for hematopoiesis and hematopoietic stem cell (HSC) function in both mice and humans. However, conventional MYSM1 knockouts cause partial embryonic lethality and growth retardation, and it is difficult to convincing...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Med Sci Monit
Main Authors: Huo, Yi, Li, Bing-Yi, Lin, Zhi-Feng, Wang, Wei, Jiang, Xiao-Xia, Chen, Xu, Xi, Wen-Jin, Li, Yu-Fang, Yang, An-Gang, Chen, Si-Yi, Wang, Tao
Format: Artigo
Jezik:Inglês
Izdano: International Scientific Literature, Inc. 2018
Teme:
Lab/In Vitro Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939948/
https://ncbi.nlm.nih.gov/pubmed/29694335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.906876
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