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Foxm1 is essential for quiescence and maintenance of hematopoietic stem cells
Foxm1, a mammalian Forkhead Box M1 protein, is known as a typical proliferation-associated transcription factor. Here, we find that Foxm1 was essential for maintenance of hematopoietic stem cell (HSC) quiescence and self-renewal capacity in vivo in mice. Reducing expression of FOXM1 also decreased q...
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| Publicado en: | Nat Immunol |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4509925/ https://ncbi.nlm.nih.gov/pubmed/26147687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3204 |
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