CCCTC-binding factor is essential to the maintenance and quiescence of hematopoietic stem cells in mice

Hematopoiesis involves a series of lineage differentiation programs initiated in hematopoietic stem cells (HSCs) found in bone marrow (BM). To ensure lifelong hematopoiesis, various molecular mechanisms are needed to maintain the HSC pool. CCCTC-binding factor (CTCF) is a DNA-binding, zinc-finger pr...

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Publicat a:Exp Mol Med
Autors principals: Kim, Tae-Gyun, Kim, Sueun, Jung, Soyeon, Kim, Mikyoung, Yang, Bobae, Lee, Min-Geol, Kim, Hyoung-Pyo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579513/
https://ncbi.nlm.nih.gov/pubmed/28857086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.124
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