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CCCTC-binding factor is essential to the maintenance and quiescence of hematopoietic stem cells in mice

Hematopoiesis involves a series of lineage differentiation programs initiated in hematopoietic stem cells (HSCs) found in bone marrow (BM). To ensure lifelong hematopoiesis, various molecular mechanisms are needed to maintain the HSC pool. CCCTC-binding factor (CTCF) is a DNA-binding, zinc-finger pr...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Kim, Tae-Gyun, Kim, Sueun, Jung, Soyeon, Kim, Mikyoung, Yang, Bobae, Lee, Min-Geol, Kim, Hyoung-Pyo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579513/
https://ncbi.nlm.nih.gov/pubmed/28857086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.124
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