The control of hematopoietic stem cell maintenance, self-renewal, and differentiation by Mysm1-mediated epigenetic regulation

Epigenetic histone modifications play critical roles in the control of self-renewal and differentiation of hematopoietic stem cells (HSCs). Mysm1 is a recently identified histone H2A deubiquitinase with essential and intrinsic roles for maintaining functional HSCs. In this study, in addition to conf...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Tao, Nandakumar, Vijayalakshmi, Jiang, Xiao-Xia, Jones, Lindsey, Yang, An-Gang, Huang, Xue F., Chen, Si-Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2013
Schlagworte:
Hematopoiesis and Stem Cells
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798996/
https://ncbi.nlm.nih.gov/pubmed/24014243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-489641
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