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Epigenetic control of dendritic cell development and fate determination of common myeloid progenitor by Mysm1

The mechanisms controlling the development of dendritic cells (DCs) remain incompletely understood. Using an Mysm1 knockout (Mysm1(−/−)) mouse model, we identified the histone H2A deubiquitinase Mysm1, as a critical regulator in DC differentiation. Mysm1(−/−) mice showed a global reduction of DCs in...

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書誌詳細
主要な著者: Won, Haejung, Nandakumar, Vijayalakshmi, Yates, Peter, Sanchez, Suzi, Jones, Lindsey, Huang, Xue F., Chen, Si-Yi
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208280/
https://ncbi.nlm.nih.gov/pubmed/25217698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-534313
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