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Epigenetic control of natural killer cell maturation by histone H2A deubiquitinase, MYSM1

Histone modifications play critical roles in regulating immunity; however, little is known about the epigenetic control of natural killer (NK) cell development. Here, we found that NK cell development is severely impaired in mice deficient in the histone H2A deubiquitinase MYSM1. We demonstrated tha...

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Detalhes bibliográficos
Main Authors: Nandakumar, Vijayalakshmi, Chou, YuChia, Zang, Linda, Huang, Xue F., Chen, Si-Yi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799335/
https://ncbi.nlm.nih.gov/pubmed/24062447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308888110
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