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Epigenetic control of natural killer cell maturation by histone H2A deubiquitinase, MYSM1

Histone modifications play critical roles in regulating immunity; however, little is known about the epigenetic control of natural killer (NK) cell development. Here, we found that NK cell development is severely impaired in mice deficient in the histone H2A deubiquitinase MYSM1. We demonstrated tha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nandakumar, Vijayalakshmi, Chou, YuChia, Zang, Linda, Huang, Xue F., Chen, Si-Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799335/
https://ncbi.nlm.nih.gov/pubmed/24062447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308888110
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