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DNA methylation and transcriptome aberrations mediated by ERα in mouse seminal vesicles following developmental DES exposure

Early transient developmental exposure to an endocrine active compound, diethylstilbestrol (DES), a synthetic estrogen, causes late-stage effects in the reproductive tract of adult mice. Estrogen receptor alpha (ERα) plays a role in mediating these developmental effects. However, the developmental m...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Li, Yin, Hamilton, Katherine J., Wang, Tianyuan, Coons, Laurel A., Jefferson, Wendy N., Li, Ruifang, Wang, Yu, Grimm, Sara A., Ramsey, J. Tyler, Liu, Liwen, Gerrish, Kevin E., Williams, Carmen J., Wade, Paul A., Korach, Kenneth S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939078/
https://ncbi.nlm.nih.gov/pubmed/29666266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719010115
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