DNA methylation and transcriptome aberrations mediated by ERα in mouse seminal vesicles following developmental DES exposure

Early transient developmental exposure to an endocrine active compound, diethylstilbestrol (DES), a synthetic estrogen, causes late-stage effects in the reproductive tract of adult mice. Estrogen receptor alpha (ERα) plays a role in mediating these developmental effects. However, the developmental m...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Li, Yin, Hamilton, Katherine J., Wang, Tianyuan, Coons, Laurel A., Jefferson, Wendy N., Li, Ruifang, Wang, Yu, Grimm, Sara A., Ramsey, J. Tyler, Liu, Liwen, Gerrish, Kevin E., Williams, Carmen J., Wade, Paul A., Korach, Kenneth S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939078/
https://ncbi.nlm.nih.gov/pubmed/29666266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719010115
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