Compartmentalized Cyclic AMP Production by the Bordetella pertussis and Bacillus anthracis Adenylate Cyclase Toxins Differentially Affects the Immune Synapse in T Lymphocytes

A central feature of the immune synapse (IS) is the tight compartmentalization of membrane receptors and signaling mediators that is functional for its ability to coordinate T cell activation. Second messengers centrally implicated in this process, such as Ca(2+) and diacyl glycerol, also undergo co...

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Publicado en:Front Immunol
Autores principales: Arumugham, Vijay B., Ulivieri, Cristina, Onnis, Anna, Finetti, Francesca, Tonello, Fiorella, Ladant, Daniel, Baldari, Cosima T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938339/
https://ncbi.nlm.nih.gov/pubmed/29765373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00919
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