The Adenylate Cyclase Toxins of Bacillus anthracis and Bordetella pertussis Promote Th2 Cell Development by Shaping T Cell Antigen Receptor Signaling

The adjuvanticity of bacterial adenylate cyclase toxins has been ascribed to their capacity, largely mediated by cAMP, to modulate APC activation, resulting in the expression of Th2–driving cytokines. On the other hand, cAMP has been demonstrated to induce a Th2 bias when present during T cell primi...

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Bibliografiset tiedot
Päätekijät: Rossi Paccani, Silvia, Benagiano, Marisa, Capitani, Nagaja, Zornetta, Irene, Ladant, Daniel, Montecucco, Cesare, D'Elios, Mario M., Baldari, Cosima T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2009
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643477/
https://ncbi.nlm.nih.gov/pubmed/19266022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000325
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