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Substituents at the C3′ and C3′N positions are critical for taxanes to overcome acquired resistance of cancer cells to paclitaxel
We tested the role of substituents at the C3′ and C3′N positions of the taxane molecule to identify taxane derivatives capable of overcoming acquired resistance to paclitaxel. Paclitaxel-resistant sublines SK-BR-3/PacR and MCF-7/PacR as well as the original paclitaxel-sensitive breast cancer cell li...
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| Vydáno v: | Toxicol Appl Pharmacol |
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| Hlavní autoři: | , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5937276/ https://ncbi.nlm.nih.gov/pubmed/29625142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2018.04.002 |
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