Fatty acid oxidation promotes reprogramming by enhancing oxidative phosphorylation and inhibiting protein kinase C

BACKGROUND: Changes in metabolic pathway preferences are key events in the reprogramming process of somatic cells to induced pluripotent stem cells (iPSCs). The optimization of metabolic conditions can enhance reprogramming; however, the detailed underlying mechanisms are largely unclear. By compari...

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Détails bibliographiques
Publié dans:Stem Cell Res Ther
Auteurs principaux: Lin, Zhaoyu, Liu, Fei, Shi, Peiliang, Song, Anying, Huang, Zan, Zou, Dayuan, Chen, Qin, Li, Jianxin, Gao, Xiang
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937047/
https://ncbi.nlm.nih.gov/pubmed/29482657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0792-6
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