CD4+ T cells memorize obesity and promote weight regain

Body weight regain often causes failure of obesity therapies while the underlying mechanism remains largely unknown. In this study, we report that immune cells, especially CD4+ T cells, mediate the ‘memory’ of previous obese status. In a weight gain-loss-regain model, we found that C57BL/6J mice wit...

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Publicado en:Cell Mol Immunol
Autores principales: Zou, Jianghuan, Lai, Beibei, Zheng, Mingzhu, Chen, Qin, Jiang, Shujun, Song, Anying, Huang, Zan, Shi, Peiliang, Tu, Xin, Wang, Di, Lu, Linrong, Lin, Zhaoyu, Gao, Xiang
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079001/
https://ncbi.nlm.nih.gov/pubmed/28626237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.36
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