Sorting nexin 27 (SNX27) regulates the trafficking and activity of the glutamine transporter ASCT2

Alanine-, serine-, cysteine-preferring transporter 2 (ASCT2, SLC1A5) is responsible for the uptake of glutamine into cells, a major source of cellular energy and a key regulator of mammalian target of rapamycin (mTOR) activation. Furthermore, ASCT2 expression has been reported in several human cance...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Yang, Zhe, Follett, Jordan, Kerr, Markus C., Clairfeuille, Thomas, Chandra, Mintu, Collins, Brett M., Teasdale, Rohan D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936802/
https://ncbi.nlm.nih.gov/pubmed/29563155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000735
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