Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2

The endosome-associated cargo adaptor sorting nexin-27 (SNX27) is linked to various neuropathologies through sorting of integral proteins to the synaptic surface, most notably AMPA receptors. To provide a broader view of SNX27-associated pathologies, we performed proteomics in rat primary neurons to...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: McMillan, Kirsty J, Banks, Paul J, Hellel, Francesca LN, Carmichael, Ruth E, Clairfeuille, Thomas, Evans, Ashley J, Heesom, Kate J, Lewis, Philip, Collins, Brett M, Bashir, Zafar I, Henley, Jeremy M, Wilkinson, Kevin A, Cullen, Peter J
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2021
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8296521/
https://ncbi.nlm.nih.gov/pubmed/34251337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59432
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