Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth

The parathyroid hormone 1 receptor (PTHR) is central to the process of bone formation and remodeling. PTHR signaling requires receptor internalization into endosomes, which is then terminated by recycling or degradation. Here we show that sorting nexin 27 (SNX27) functions as an adaptor that couples...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Chan, Audrey S. M., Clairfeuille, Thomas, Landao-Bassonga, Euphemie, Kinna, Genevieve, Ng, Pei Ying, Loo, Li Shen, Cheng, Tak Sum, Zheng, Minghao, Hong, Wanjin, Teasdale, Rohan D., Collins, Brett M., Pavlos, Nathan J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831889/
https://ncbi.nlm.nih.gov/pubmed/26912788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-12-0851
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