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Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth
The parathyroid hormone 1 receptor (PTHR) is central to the process of bone formation and remodeling. PTHR signaling requires receptor internalization into endosomes, which is then terminated by recycling or degradation. Here we show that sorting nexin 27 (SNX27) functions as an adaptor that couples...
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| Publié dans: | Mol Biol Cell |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4831889/ https://ncbi.nlm.nih.gov/pubmed/26912788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-12-0851 |
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