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Pathways for maintenance of telomeres and common fragile sites during DNA replication stress

Oncogene activation during tumour development leads to changes in the DNA replication programme that enhance DNA replication stress. Certain regions of the human genome, such as common fragile sites and telomeres, are particularly sensitive to DNA replication stress due to their inherently ‘difficul...

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Detaylı Bibliyografya
Yayımlandı:Open Biol
Asıl Yazarlar: Özer, Özgün, Hickson, Ian D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Royal Society 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936717/
https://ncbi.nlm.nih.gov/pubmed/29695617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.180018
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