The SNM1B/APOLLO DNA nuclease functions in resolution of replication stress and maintenance of common fragile site stability

SNM1B/Apollo is a DNA nuclease that has important functions in telomere maintenance and repair of DNA interstrand crosslinks (ICLs) within the Fanconi anemia (FA) pathway. SNM1B is required for efficient localization of key repair proteins, such as the FA protein, FANCD2, to sites of ICL damage and...

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Autors principals: Mason, Jennifer M., Das, Ishita, Arlt, Martin, Patel, Neil, Kraftson, Stephanie, Glover, Thomas W., Sekiguchi, JoAnn M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836474/
https://ncbi.nlm.nih.gov/pubmed/23863462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt340
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