Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1

Inositol hexakisphosphate kinase-1 (IP6K1) is required for male fertility, but the underlying mechanisms have been elusive. Here, we report that IP6K1 is required for multiple aspects of male germ cell development. This development requires selective interactions between germ cells and Sertoli cells...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Fu, Chenglai, Rojas, Tomas, Chin, Alfred C., Cheng, Weiwei, Bernstein, Isaac A., Albacarys, Lauren K., Wright, William W., Snyder, Solomon H.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935691/
https://ncbi.nlm.nih.gov/pubmed/29728588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25468-8
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