Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1

Inositol hexakisphosphate kinase-1 (IP6K1) is required for male fertility, but the underlying mechanisms have been elusive. Here, we report that IP6K1 is required for multiple aspects of male germ cell development. This development requires selective interactions between germ cells and Sertoli cells...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fu, Chenglai, Rojas, Tomas, Chin, Alfred C., Cheng, Weiwei, Bernstein, Isaac A., Albacarys, Lauren K., Wright, William W., Snyder, Solomon H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935691/
https://ncbi.nlm.nih.gov/pubmed/29728588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25468-8
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