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IRF8 regulates transcription of Naips for NLRC4 inflammasome activation
Inflammasome activation is critical for host defense against various microbial infections. Activation of the NLRC4 inflammasome requires detection of flagellin or type III secretion system (T3SS) components by NLR family apoptosis inhibitory proteins (NAIPs); yet how this pathway is regulated is unk...
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| Pubblicato in: | Cell |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5935577/ https://ncbi.nlm.nih.gov/pubmed/29576451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.02.055 |
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