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Genetics of coronary artery disease: discovery, biology and clinical translation

Coronary artery disease is the leading global cause of mortality. Long recognized to be heritable, recent advances have started to unravel the genetic architecture of the disease. Common variant association studies have linked about 60 genetic loci to coronary risk. Large-scale gene sequencing effor...

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Detalles Bibliográficos
Publicado en:Nat Rev Genet
Autores principales: Khera, Amit V., Kathiresan, Sekar
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935119/
https://ncbi.nlm.nih.gov/pubmed/28286336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg.2016.160
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