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Genetics of coronary artery disease: discovery, biology and clinical translation

Coronary artery disease is the leading global cause of mortality. Long recognized to be heritable, recent advances have started to unravel the genetic architecture of the disease. Common variant association studies have linked about 60 genetic loci to coronary risk. Large-scale gene sequencing effor...

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Detalhes bibliográficos
Publicado no:Nat Rev Genet
Main Authors: Khera, Amit V., Kathiresan, Sekar
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935119/
https://ncbi.nlm.nih.gov/pubmed/28286336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg.2016.160
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