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Residues contributing to drug transport by ABCG2 are localised to multiple drug-binding pockets
Multidrug binding and transport by the ATP-binding cassette transporter ABCG2 is a factor in the clinical resistance to chemotherapy in leukaemia, and a contributory factor to the pharmacokinetic profiles of many other prescribed drugs. Despite its importance, the structural basis of multidrug trans...
Guardat en:
| Publicat a: | Biochem J |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Portland Press Ltd.
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5934980/ https://ncbi.nlm.nih.gov/pubmed/29661915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170923 |
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