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On-chip measurements of protein unfolding from direct observations of micron-scale diffusion
Investigations of protein folding, unfolding and stability are critical for the understanding of the molecular basis of biological structure and function. We describe here a microfluidic approach to probe the unfolding of unlabelled protein molecules in microliter volumes. We achieve this objective...
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| Veröffentlicht in: | Chem Sci |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Royal Society of Chemistry
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5934698/ https://ncbi.nlm.nih.gov/pubmed/29780480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc04331g |
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