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Unstructured 5′-tails act through ribosome standby to override inhibitory structure at ribosome binding sites

Initiation is the rate-limiting step in translation. It is well-known that stable structure at a ribosome binding site (RBS) impedes initiation. The ribosome standby model of de Smit and van Duin, based on studies of the MS2 phage coat cistron, proposed how high translation rates can be reconciled w...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Sterk, Maaike, Romilly, Cédric, Wagner, E Gerhart H
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934652/
https://ncbi.nlm.nih.gov/pubmed/29420821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky073
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