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Unstructured 5′-tails act through ribosome standby to override inhibitory structure at ribosome binding sites

Initiation is the rate-limiting step in translation. It is well-known that stable structure at a ribosome binding site (RBS) impedes initiation. The ribosome standby model of de Smit and van Duin, based on studies of the MS2 phage coat cistron, proposed how high translation rates can be reconciled w...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Sterk, Maaike, Romilly, Cédric, Wagner, E Gerhart H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934652/
https://ncbi.nlm.nih.gov/pubmed/29420821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky073
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