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Unstructured 5′-tails act through ribosome standby to override inhibitory structure at ribosome binding sites

Initiation is the rate-limiting step in translation. It is well-known that stable structure at a ribosome binding site (RBS) impedes initiation. The ribosome standby model of de Smit and van Duin, based on studies of the MS2 phage coat cistron, proposed how high translation rates can be reconciled w...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Sterk, Maaike, Romilly, Cédric, Wagner, E Gerhart H
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934652/
https://ncbi.nlm.nih.gov/pubmed/29420821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky073
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