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An RNA pseudoknot is essential for standby-mediated translation of the tisB toxin mRNA in Escherichia coli

In response to DNA damage, Escherichia coli cells activate the expression of the toxin gene tisB of the toxin–antitoxin system tisB-istR1. Of three isoforms, only the processed, highly structured +42 tisB mRNA is active. Translation requires a standby site, composed of two essential elements: a sing...

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Publicat a:Nucleic Acids Res
Autors principals: Romilly, Cédric, Lippegaus, Anne, Wagner, E Gerhart H
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708055/
https://ncbi.nlm.nih.gov/pubmed/33231643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1139
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