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Translation rate is controlled by coupled trade-offs between site accessibility, selective RNA unfolding and sliding at upstream standby sites

The ribosome’s interactions with mRNA govern its translation rate and the effects of post-transcriptional regulation. Long, structured 5′ untranslated regions (5′ UTRs) are commonly found in bacterial mRNAs, though the physical mechanisms that determine how the ribosome binds these upstream regions...

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Détails bibliographiques
Auteurs principaux: Espah Borujeni, Amin, Channarasappa, Anirudh S., Salis, Howard M.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
RNA
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936740/
https://ncbi.nlm.nih.gov/pubmed/24234441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1139
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