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mTOR referees memory and disease through mRNA repression and competition
Mammalian target of rapamycin (mTOR) activity is required for memory and is dysregulated in disease. Activation of mTOR promotes protein synthesis; however, new studies are demonstrating that mTOR activity also represses the translation of mRNAs. Almost three decades ago, Kandel and colleagues hypot...
Gardado en:
| Publicado en: | FEBS Lett |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5933947/ https://ncbi.nlm.nih.gov/pubmed/28493559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12675 |
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