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mTOR referees memory and disease through mRNA repression and competition
Mammalian target of rapamycin (mTOR) activity is required for memory and is dysregulated in disease. Activation of mTOR promotes protein synthesis; however, new studies are demonstrating that mTOR activity also represses the translation of mRNAs. Almost three decades ago, Kandel and colleagues hypot...
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| 發表在: | FEBS Lett |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5933947/ https://ncbi.nlm.nih.gov/pubmed/28493559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12675 |
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