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Molecular structures of cdc2-like kinases in complex with a new inhibitor chemotype
Cdc2-like kinases (CLKs) represent a family of serine-threonine kinases involved in the regulation of splicing by phosphorylation of SR-proteins and other splicing factors. Although compounds acting against CLKs have been described, only a few show selectivity against dual-specificity tyrosine phosp...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5933782/ https://ncbi.nlm.nih.gov/pubmed/29723265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196761 |
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