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[b]-Annulated Halogen-Substituted Indoles as Potential DYRK1A Inhibitors
Since hyperactivity of the protein kinase DYRK1A is linked to several neurodegenerative disorders, DYRK1A inhibitors have been suggested as potential therapeutics for Down syndrome and Alzheimer’s disease. Most published inhibitors to date suffer from low selectivity against related kinases or from...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6891749/ https://ncbi.nlm.nih.gov/pubmed/31766108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24224090 |
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