Structure elucidation and quantification of the reduction products of anticancer Pt(iv) prodrugs by electrochemistry/mass spectrometry (EC-MS)

Pt(iv) prodrugs are a class of promising anticancer agents, which are activated by reduction to the active Pt(ii) species. Consequently, the reduction process is a crucial parameter. Herein, a new approach using electrochemistry (EC) coupled to liquid chromatography (LC) and electrospray ionization-...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Analyst
Prif Awduron: Frensemeier, L. M., Mayr, J., Koellensperger, G., Keppler, B. K., Kowol, C. R., Karst, U.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Royal Society of Chemistry 2018
Pynciau:
Chemistry
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933000/
https://ncbi.nlm.nih.gov/pubmed/29629473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8an00258d
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