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Comparison of metabolic pathways of different α-N-heterocyclic thiosemicarbazones
Clinical failure of novel drugs is often related to their rapid metabolism and excretion. This highlights the importance of elucidation of their pharmacokinetic profile already at the preclinical stage of drug development. Triapine, the most prominent representative of α-N-heterocyclic thiosemicarba...
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| Publicado no: | Anal Bioanal Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5849672/ https://ncbi.nlm.nih.gov/pubmed/29476231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-018-0889-x |
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