Serum-binding properties of isosteric ruthenium and osmium anticancer agents elucidated by SEC–ICP–MS

ABSTRACT: Size-exclusion chromatography–inductively coupled plasma–mass spectrometry (SEC–ICP–MS) was used to study the serum-binding preferences of two metallodrugs with anticancer activities in vivo, namely the organoruthenium compound plecstatin-1 and its isosteric osmium analog. The complexes we...

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Bibliografski detalji
Izdano u:Monatsh Chem
Glavni autori: Klose, Matthias H. M., Schöberl, Anna, Heffeter, Petra, Berger, Walter, Hartinger, Christian G., Koellensperger, Gunda, Meier-Menches, Samuel M., Keppler, Bernhard K.
Format: Artigo
Jezik:Inglês
Izdano: Springer Vienna 2018
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Original Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133104/
https://ncbi.nlm.nih.gov/pubmed/30237619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-018-2280-1
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