Metal–Arene Complexes with Indolo[3,2-c]-quinolines: Effects of Ruthenium vs Osmium and Modifications of the Lactam Unit on Intermolecular Interactions, Anticancer Activity, Cell Cycle, and Cellular Accumulation

[Image: see text] Six novel ruthenium(II)– and osmium(II)–arene complexes with three modified indolo[3,2-c]quinolines have been synthesized in situ starting from 2-aminoindoloquinolines and 2-pyridinecarboxaldehyde in the presence of [M(p-cymene)Cl(2)](2) (M = Ru, Os) in ethanol. All complexes have...

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Detalhes bibliográficos
Main Authors: Filak, Lukas K., Göschl, Simone, Heffeter, Petra, Ghannadzadeh Samper, Katia, Egger, Alexander E., Jakupec, Michael A., Keppler, Bernhard K., Berger, Walter, Arion, Vladimir B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573711/
https://ncbi.nlm.nih.gov/pubmed/23431223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/om3012272
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