L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis

The retrotransposon Long Interspersed Element 1 (LINE-1 or L1) is a continuing source of germline and somatic mutagenesis in mammals. Deregulated L1 activity is a hallmark of cancer, and L1 mutagenesis has been described in numerous human malignancies. We previously employed retrotransposon capture...

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Détails bibliographiques
Publié dans:Genome Res
Auteurs principaux: Schauer, Stephanie N., Carreira, Patricia E., Shukla, Ruchi, Gerhardt, Daniel J., Gerdes, Patricia, Sanchez-Luque, Francisco J., Nicoli, Paola, Kindlova, Michaela, Ghisletti, Serena, Santos, Alexandre Dos, Rapoud, Delphine, Samuel, Didier, Faivre, Jamila, Ewing, Adam D., Richardson, Sandra R., Faulkner, Geoffrey J.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932605/
https://ncbi.nlm.nih.gov/pubmed/29643204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.226993.117
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