Hydrostatic pressure suppresses fibrotic changes via Akt/GSK‐3 signaling in human cardiac fibroblasts

Mechanical stresses play important roles in the process of constructing and modifying heart structure. It has been well established that stretch force acting on cardiac fibroblasts induces fibrosis. However, the effects of compressive force, that is, hydrostatic pressure (HP), have not been well elu...

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Sparad:
Bibliografiska uppgifter
I publikationen:Physiol Rep
Huvudupphovsmän: Tanaka, Ryo, Umemura, Masanari, Narikawa, Masatoshi, Fujita, Takayuki, Yokoyama, Utako, Ishigami, Tomoaki, Kimura, Kazuo, Tamura, Kouichi, Ishikawa, Yoshihiro
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2018
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932570/
https://ncbi.nlm.nih.gov/pubmed/29722156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13687
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