Acute Hyperthermia Inhibits TGF-β1-induced Cardiac Fibroblast Activation via Suppression of Akt Signaling

Transforming growth factor-β1 (TGF-β1) induces phenotypic changes in fibroblasts to become myofibroblasts with increased production of extracellular matrix (ECM) components and cytokines. It is also known that excessive activation of myofibroblasts accelerates cardiac fibrosis, remodeling, and thus...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Narikawa, Masatoshi, Umemura, Masanari, Tanaka, Ryo, Fujita, Takayuki, Yokoyama, Utako, Ishigami, Tomoaki, Kimura, Kazuo, Tamura, Kouichi, Ishikawa, Yoshihiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908876/
https://ncbi.nlm.nih.gov/pubmed/29674727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24749-6
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